Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+

Hongxia Sun; Junfeng Xiang; Wei Gai; Yan Liu; Aijiao Guan; Qianfan Yang; Qian Li; Qian Shang; Hui Su; Yalin Tang; Guangzhi Xu

doi:10.1039/C3CC39020A

Quantification of the Na⁺/K⁺ ratio based on the different response of a newly identified G-quadruplex to Na⁺ and K⁺†

Hongxia Sun,^ab Junfeng Xiang,^a Wei Gai,^ab Yan Liu,^a Aijiao Guan,^a Qianfan Yang,^a Qian Li,^a Qian Shang,^a Hui Su,^a Yalin Tang*^a and Guangzhi Xu^a

Author affiliations

* Corresponding authors

^a National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Zhongguancun North 1st street 2, Beijing 100190, P. R. China
E-mail: tangyl@iccas.ac.cn

^b University of the Chinese Academy of Sciences, Yuquan Road 19(A), Shijingshan District, Beijing 100049, P. R. China

Abstract

A G-quadruplex is identified which can exhibit two different motifs, respectively, corresponding to Na⁺ and K⁺. The relative amount of each motif is related to the Na⁺/K⁺ ratio. Based on selective recognition of the G-quadruplex motifs by a cyanine dye aggregate, a method for both colorimetric and quantitative measurements of Na⁺/K⁺ ratios is constructed.

Chemical Communications

Quantification of the Na⁺/K⁺ ratio based on the different response of a newly identified G-quadruplex to Na⁺ and K⁺†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Quantification of the Na⁺/K⁺ ratio based on the different response of a newly identified G-quadruplex to Na⁺ and K⁺

Social activity

Search articles by author

Spotlight

Advertisements

Chemical Communications

Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+

Social activity

Search articles by author

Spotlight

Advertisements

Quantification of the Na⁺/K⁺ ratio based on the different response of a newly identified G-quadruplex to Na⁺ and K⁺†

Quantification of the Na⁺/K⁺ ratio based on the different response of a newly identified G-quadruplex to Na⁺ and K⁺