Issue 33, 2013
From the journal:

Chemical Communications

A chemiluminescence imaging array for the detection of cancer cells by dual-aptamer recognition and bio-bar-code nanoprobe-based rolling circle amplification†

Sai Bi,a   Bin Ji,a   Zhipeng Zhanga  and  Shusheng Zhang*a  

* Corresponding authors

a Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China
E-mail: shushzhang@126.com
Fax: +86 532 84022750
Tel: +86 532 84022750

Abstract

A chemiluminescence imaging array was developed for Ramos cell detection by employing a HRP-labeled bio-bar-code AuNP probe to amplify signals and dual-aptamer recognition to improve specificity, achieving high throughput, easy operation, rapid analysis, and high sensitivity for cancer cells.

Graphical abstract: A chemiluminescence imaging array for the detection of cancer cells by dual-aptamer recognition and bio-bar-code nanoprobe-based rolling circle amplification

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Article information

DOI
https://doi.org/10.1039/C3CC39296A
Article type
Communication
Submitted
31 Dec 2012
Accepted
07 Mar 2013
First published
08 Mar 2013

Chem. Commun., 2013,49, 3452-3454

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A chemiluminescence imaging array for the detection of cancer cells by dual-aptamer recognition and bio-bar-code nanoprobe-based rolling circle amplification

S. Bi, B. Ji, Z. Zhang and S. Zhang, Chem. Commun., 2013, 49, 3452 DOI: 10.1039/C3CC39296A

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