Issue 33, 2013
From the journal:

Chemical Communications

Efficient construction of highly functionalized spiro[γ-butyrolactone-pyrrolidin-3,3′-oxindole] tricyclic skeletons via an organocatalytic 1,3-dipolar cycloaddition†

Long Wang,‡a   Xiao-Mei Shi,‡a   Wei-Ping Dong,a   Li-Ping Zhua  and  Rui Wang*ab  

* Corresponding authors

a Key Laboratory of Preclinical Study for New Drugs of Gansu Province, State Key Laboratory of Applied Organic Chemistry, School of Life Sciences, School of Basic Medical Science, Lanzhou University, Lanzhou 730000, China
E-mail: wangrui@lzu.edu.cn

b Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China
E-mail: bcrwang@polyu.edu.hk

Abstract

Highly functionalized spiro[γ-butyrolactone-pyrrolidin-3,3′-oxindole] tricyclic skeletons were delivered successfully with high optical purity using an effective yet simple procedure.

Graphical abstract: Efficient construction of highly functionalized spiro[γ-butyrolactone-pyrrolidin-3,3′-oxindole] tricyclic skeletons via an organocatalytic 1,3-dipolar cycloaddition

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Article information

DOI
https://doi.org/10.1039/C3CC40669E
Article type
Communication
Submitted
26 Jan 2013
First published
01 Mar 2013

Chem. Commun., 2013,49, 3458-3460

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Efficient construction of highly functionalized spiro[γ-butyrolactone-pyrrolidin-3,3′-oxindole] tricyclic skeletons via an organocatalytic 1,3-dipolar cycloaddition

L. Wang, X. Shi, W. Dong, L. Zhu and R. Wang, Chem. Commun., 2013, 49, 3458 DOI: 10.1039/C3CC40669E

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