Issue 52, 2013
From the journal:

Chemical Communications

A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase activity based on exonuclease-mediated amplification†

Cuihua Chen,a   Dianming Zhou,a   Hao Tang,*a   Manfen Lianga  and  Jianhui Jiang*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China
E-mail: haotang@hnu.edu.cn, jianhuijiang@hnu.edu.cn
Fax: +86 731 88821916
Tel: +86 731 88821916

Abstract

A novel homogeneous fluorescence assay strategy for highly sensitive detection of thymine DNA glycosylase (TDG) enzyme activity based on the exonuclease-mediated signal amplification reaction was reported.

Graphical abstract: A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase activity based on exonuclease-mediated amplification

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Article information

DOI
https://doi.org/10.1039/C3CC41700J
Article type
Communication
Submitted
06 Mar 2013
Accepted
08 May 2013
First published
09 May 2013

Chem. Commun., 2013,49, 5874-5876

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A sensitive, homogeneous fluorescence assay for detection of thymine DNA glycosylase activity based on exonuclease-mediated amplification

C. Chen, D. Zhou, H. Tang, M. Liang and J. Jiang, Chem. Commun., 2013, 49, 5874 DOI: 10.1039/C3CC41700J

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