Issue 48, 2013
From the journal:

Chemical Communications

G-quadruplex formation of entirely hydrophobic DNA in organic solvents†

Tomonori Shibata,a   Chikara Dohno*ab  and  Kazuhiko Nakatani*a  

* Corresponding authors

a The Institute of Scientific and Industrial Research (ISIR), Osaka University, Ibaraki 567-0047, Japan
E-mail: cdohno@sanken.osaka-u.ac.jp, nakatani@sanken.osaka-u.ac.jp
Fax: +81-6-6879-8459
Tel: +81-6-6879-8457

b PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan

Abstract

We report herein a novel hydrophobic G-quadruplex DNA consisting of dodecyl phosphotriester linkages. The 6-mer hydrophobic DNA having a TG4T sequence binds to monovalent cations to form a tetramolecular G-quadruplex in low polarity organic solvents.

Graphical abstract: G-quadruplex formation of entirely hydrophobic DNA in organic solvents

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Article information

DOI
https://doi.org/10.1039/C3CC42221F
Article type
Communication
Submitted
27 Mar 2013
Accepted
25 Apr 2013
First published
25 Apr 2013

Chem. Commun., 2013,49, 5501-5503

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G-quadruplex formation of entirely hydrophobic DNA in organic solvents

T. Shibata, C. Dohno and K. Nakatani, Chem. Commun., 2013, 49, 5501 DOI: 10.1039/C3CC42221F

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