Issue 57, 2013
From the journal:

Chemical Communications

Copper-catalyzed annulation of amidines for quinazoline synthesis†

Yunhe Lv,a   Yan Li,a   Tao Xiong,*a   Weiya Pu,a   Hongwei Zhang,a   Kai Sun,a   Qun Liua  and  Qian Zhang*a  

* Corresponding authors

a Department of Chemistry, Northeast Normal University, Changchun, China
E-mail: xiongt626@nenu.edu.cn, zhangq651@nenu.edu.cn
Fax: +86-431-5099759

Abstract

An efficient Cu-catalyzed synthesis of quinazolines via the C–N bond formation reactions between N–H bonds of amidines and C(sp3)–H bonds adjacent to sulfur or nitrogen atoms in the commonly used solvents, such as DMSO, DMF, DMA, NMP or TMEDA, followed by intramolecular C–C bond formation reactions was developed for the first time.

Graphical abstract: Copper-catalyzed annulation of amidines for quinazoline synthesis

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC43129K
Article type
Communication
Submitted
27 Apr 2013
Accepted
25 May 2013
First published
30 May 2013

Chem. Commun., 2013,49, 6439-6441

Permissions

Request permissions

Copper-catalyzed annulation of amidines for quinazoline synthesis

Y. Lv, Y. Li, T. Xiong, W. Pu, H. Zhang, K. Sun, Q. Liu and Q. Zhang, Chem. Commun., 2013, 49, 6439 DOI: 10.1039/C3CC43129K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements