Issue 77, 2013
From the journal:

Chemical Communications

Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene†

Yuan Zou,a   Jie Chen,a   Zhi Zhu,a   Lianyu Lu,a   Yishun Huang,a   Yanling Song,a   Huimin Zhang,a   Huaizhi Kanga  and  Chaoyong James Yang*a  

* Corresponding authors

a The Key Laboratory of Analytical Science, Key Laboratory for Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
E-mail: cyyang@xmu.edu.cn

Abstract

A pair of single-molecule photo-responsive DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity was designed and fabricated. Compared with other DNA nanomachines, our DNA nanoscissors have the advantages of a clean switching mechanism, as well as robust and highly reversible operation.

Graphical abstract: Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene

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Article information

DOI
https://doi.org/10.1039/C3CC44188A
Article type
Communication
Submitted
04 Jun 2013
Accepted
26 Jul 2013
First published
29 Jul 2013

Chem. Commun., 2013,49, 8716-8718

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Single-molecule photon-fueled DNA nanoscissors for DNA cleavage based on the regulation of substrate binding affinity by azobenzene

Y. Zou, J. Chen, Z. Zhu, L. Lu, Y. Huang, Y. Song, H. Zhang, H. Kang and C. J. Yang, Chem. Commun., 2013, 49, 8716 DOI: 10.1039/C3CC44188A

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