Issue 13, 2014
From the journal:

Chemical Communications

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids†

Meihua Yu,‡a   Surajit Karmakar,‡a   Jie Yang,a   Hongwei Zhang,a   Yannan Yang,a   Peter Thornb  and  Chengzhong Yu*a  

* Corresponding authors

a Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia
E-mail: c.yu@uq.edu.au
Fax: +61-7-334-63973
Tel: +61-7-334-63283

b School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia

Abstract

A facile approach has been developed to prepare ultra-small hybrid silica spheres with a diameter of ∼10 nm, which show highly enhanced penetration ability in 3D glioma spheroids compared to conventional mesoporous silica nanoparticles.

Graphical abstract: Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids

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Article information

DOI
https://doi.org/10.1039/C3CC48416E
Article type
Communication
Submitted
03 Nov 2013
Accepted
26 Nov 2013
First published
27 Nov 2013

Chem. Commun., 2014,50, 1527-1529

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Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids

M. Yu, S. Karmakar, J. Yang, H. Zhang, Y. Yang, P. Thorn and C. Yu, Chem. Commun., 2014, 50, 1527 DOI: 10.1039/C3CC48416E

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