Issue 4, 2014

Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions

Abstract

A clean and efficient method for the domino synthesis of new functionalized benzofuro[2,3-c]pyridines from easily accessible 2-hydroxychalcones, α-bromo ketones and ammonium acetate is described. Furan and pyridine ring moieties are ingeniously formed in a one-pot operation in this tricyclic system.

Graphical abstract: Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions

Supplementary files

Article information

Article type
Paper
Submitted
30 Oct 2013
Accepted
09 Jan 2014
First published
10 Jan 2014

Green Chem., 2014,16, 2213-2218

Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions

Y. Rao, Z. Li and G. Yin, Green Chem., 2014, 16, 2213 DOI: 10.1039/C3GC42234H

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