Issue 1, 2014
From the journal:

Materials Horizons

Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles†

Krishnendu Saha,‡a   Daniel F. Moyano‡a  and  Vincent M. Rotello*a  

* Corresponding authors

a Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant St, Amherst, Massachusetts, USA 01003
E-mail: rotello@chem.umass.edu
Fax: +413-545-4490
Tel: +413-545-2058

Abstract

The role of nanoparticle surface hydrophobicity on hemolytic properties is established in the absence and presence of plasma proteins. Significantly, the formation of a plasma protein corona on the NP surface protects red blood cells from both hydrophilic and hydrophobic NP-mediated hemolysis.

Graphical abstract: Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles

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Article information

DOI
https://doi.org/10.1039/C3MH00075C
Article type
Communication
Submitted
01 Aug 2013
Accepted
27 Sep 2013
First published
27 Sep 2013

Mater. Horiz., 2014,1, 102-105

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Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles

K. Saha, D. F. Moyano and V. M. Rotello, Mater. Horiz., 2014, 1, 102 DOI: 10.1039/C3MH00075C

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