Issue 4, 2013
From the journal:

New Journal of Chemistry

A mild entry to isoindolinones from furfural as renewable resource†

Gilles Caillot,ab   Shridhar Hegdec  and  Emmanuel Gras*ab  

* Corresponding authors

a CNRS, LCC (Laboratoire de Chimie de Coordination), 205 route de Narbonne, BP 44099, F-31077 Toulouse Cedex 4, France

b Université de Toulouse, UPS, INPT, F-31077 Toulouse Cedex 4, France
E-mail: emmanuel.gras@lcc-toulouse.fr

c Pennakem, 3324 Chelsea Avenue Memphis, USA

Abstract

A convenient transformation of furfural and derivatives into arene compounds is described. This process provides a straightforward access to isoindolinones from a renewable resource via the sequence of a tandem Ugi–Diels–Alder process followed by a ring-opening, dehydrating aromatisation. Five bonds are created and water is the sole by-product during this two-step sequence.

Graphical abstract: A mild entry to isoindolinones from furfural as renewable resource

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Article information

DOI
https://doi.org/10.1039/C3NJ41050A
Article type
Paper
Submitted
19 Nov 2012
Accepted
23 Jan 2013
First published
24 Jan 2013

New J. Chem., 2013,37, 1195-1200

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A mild entry to isoindolinones from furfural as renewable resource

G. Caillot, S. Hegde and E. Gras, New J. Chem., 2013, 37, 1195 DOI: 10.1039/C3NJ41050A

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