Issue 5, 2014
From the journal:

Natural Product Reports

Fungal phenalenones: chemistry, biology, biosynthesis and phylogeny

Mahmoud F. Elsebai,*abc   Muhammad Saleem,*d   Mysore V. Tejesvi,b   Marena Kajula,c   Sampo Mattila,*c   Mohamed Mehiri,*e   Ari Turpeinenc  and  Anna Maria Pirttilä*b  

* Corresponding authors

a Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Egypt
E-mail: elsebai72@yahoo.com

b Department of Biology, University of Oulu, PO Box 3000, FIN-90014 Oulu, Finland
E-mail: am.pirttila@oulu.fi

c Department of Chemistry, University of Oulu, PO Box 3000, FIN-90014 Oulu, Finland
E-mail: sampo.mattila@oulu.fi

d Department of Chemistry, Baghdad-ul-Jadeed Campus, the Islamia University of Bahawalpur, 63100-Bahawalpur, Pakistan
E-mail: drsaleem_kr@yahoo.com

e Nice Institute of Chemistry, UMR CNRS 7272, Marine Natural products team, UFR of Sciences, University Nice Sophia Antipolis, France
E-mail: Mohamed.MEHIRI@unice.fr

Abstract

Covering up to the end of August 2013

Phenalenones are members of a unique class of natural polyketides exhibiting diverse biological potential. This is a comprehensive review of 72 phenalenones with diverse structural features originating from fungal sources. Their bioactive potential and structure elucidation are discussed along with a review of their biosynthetic pathways and the taxonomical relationship between the fungi producing these natural products.

Graphical abstract: Fungal phenalenones: chemistry, biology, biosynthesis and phylogeny

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Article information

DOI
https://doi.org/10.1039/C3NP70088G
Article type
Review Article
Submitted
12 Sep 2013
First published
01 Apr 2014

Nat. Prod. Rep., 2014,31, 628-645

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Fungal phenalenones: chemistry, biology, biosynthesis and phylogeny

M. F. Elsebai, M. Saleem, M. V. Tejesvi, M. Kajula, S. Mattila, M. Mehiri, A. Turpeinen and A. M. Pirttilä, Nat. Prod. Rep., 2014, 31, 628 DOI: 10.1039/C3NP70088G

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