Issue 18, 2013

An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

Abstract

A mild and efficient synthesis of bicyclic oxazolidinones from quinols and isocyanates, under DBU-mediated conditions at room temperature, is described. The aza-Michael addition to substituted cyclohexadienones is stereoselective and chemoselective.

Graphical abstract: An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

Supplementary files

Article information

Article type
Communication
Submitted
09 Jan 2013
Accepted
09 Mar 2013
First published
12 Mar 2013

Org. Biomol. Chem., 2013,11, 2939-2942

An expedient stereoselective and chemoselective synthesis of bicyclic oxazolidinones from quinols and isocyanates

J. Zhang, J. Wu, Z. Yin, H. Zeng, K. Khanna, C. Hu and S. Zheng, Org. Biomol. Chem., 2013, 11, 2939 DOI: 10.1039/C3OB00047H

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