Issue 28, 2013
From the journal:

Organic & Biomolecular Chemistry

Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate†

Dongjian Zhu,ab   Guoping Li,ab   Lin Xue*a  and  Hua Jiang*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, P.R. China
E-mail: hjiang@iccas.ac.cn, zinclin@iccas.ac.cn
Tel: (+86) 10-82612075

b University of Chinese Academy of Sciences, Beijing, P.R. China

Abstract

We report a facile method to design NIR ratiometric fluorescent probes in terms of analyte-induced carbamate cleavage. Two examples, CyNB and CyNN3, exhibit a significant analyte-triggered response with ratiometric fluorescence change in the NIR range and dual-emission ratiometry in living cells.

Graphical abstract: Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate

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Article information

DOI
https://doi.org/10.1039/C3OB40932E
Article type
Communication
Submitted
03 May 2013
Accepted
28 May 2013
First published
29 May 2013

Org. Biomol. Chem., 2013,11, 4577-4580

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Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate

D. Zhu, G. Li, L. Xue and H. Jiang, Org. Biomol. Chem., 2013, 11, 4577 DOI: 10.1039/C3OB40932E

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