Issue 20, 2013

Synthesis of a new conjugated polymer for cell membrane imaging by using an intracellular targeting strategy

Abstract

A water soluble polythiophene with tyrosine kinase inhibitor lapatinib as side chain moieties (PTL) was designed and synthesized. Together with its fluorescent characteristic and low cytotoxicity, PTL can be used for cell membrane imaging of living cells by targeting the intracellular domain of transmembrane proteins.

Graphical abstract: Synthesis of a new conjugated polymer for cell membrane imaging by using an intracellular targeting strategy

Supplementary files

Article information

Article type
Communication
Submitted
21 Jan 2013
Accepted
24 Feb 2013
First published
25 Feb 2013

Polym. Chem., 2013,4, 5212-5215

Synthesis of a new conjugated polymer for cell membrane imaging by using an intracellular targeting strategy

B. Wang, C. Zhu, L. Liu, F. Lv, Q. Yang and S. Wang, Polym. Chem., 2013, 4, 5212 DOI: 10.1039/C3PY00097D

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