Issue 17, 2013
From the journal:

RSC Advances

Peptide nucleic acids are an additional class of aptamers†

Eun Jeong Lee,a   Hyun Kyung Lim,a   Yea Seul Choa  and  Sang Soo Hah*a  

* Corresponding authors

a Department of Chemistry and Research Institute for Basic Sciences, Kyung Hee University, Seoul 130-701, Korea
E-mail: sshah@khu.ac.kr

Abstract

Peptide nucleic acids (PNAs) have been known for their similar or superior properties to DNA or RNA since 1991, but not regarded as a separate class of aptamers. We report here an interesting additional property of PNAs revealed by graphene oxide (GO)-based assays, suggesting that nucleobases in certain aptamers play more important roles in strong and selective binding to the target molecules.

Graphical abstract: Peptide nucleic acids are an additional class of aptamers

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Article information

DOI
https://doi.org/10.1039/C3RA40553B
Article type
Communication
Submitted
31 Jan 2013
Accepted
06 Mar 2013
First published
06 Mar 2013

RSC Adv., 2013,3, 5828-5831

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Peptide nucleic acids are an additional class of aptamers

E. J. Lee, H. K. Lim, Y. S. Cho and S. S. Hah, RSC Adv., 2013, 3, 5828 DOI: 10.1039/C3RA40553B

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