Issue 32, 2013

A novel pH “off–on” fluorescent probe for lysosome imaging

Abstract

In the present paper, a new pH sensitive fluorescent probe based on a 4-acylated naphthalimide fluorophore was well designed and synthesized. It has a high specificity for lysosomes over other cell organelles. The intrinsic high signal to noise ratio in cell imaging, broad Stokes shift and practical fluorescence quantum yield of this probe will ensure its prominent position in the intracellular lysosome targeting and imaging toolbox.

Graphical abstract: A novel pH “off–on” fluorescent probe for lysosome imaging

Supplementary files

Article information

Article type
Paper
Submitted
18 Apr 2013
Accepted
31 May 2013
First published
31 May 2013

RSC Adv., 2013,3, 13412-13416

A novel pH “off–on” fluorescent probe for lysosome imaging

L. Chen, J. Li, Z. Liu, Z. Ma, W. Zhang, L. Du, W. Xu, H. Fang and M. Li, RSC Adv., 2013, 3, 13412 DOI: 10.1039/C3RA41898G

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