A photosensitization-based approach for a convenient and efficient conversion of aldoximes and primary amides into nitriles is reported. The protocol involves eosin Y catalysed, visible-light-mediated in situ formation of the Vilsmeier–Haack reagent from CBr4 and a catalytic amount of DMF, which brings about the desired transformation to afford nitriles at r.t.
A. K. Yadav, V. P. Srivastava and L. D. S. Yadav, RSC Adv., 2014, 4, 4181 DOI: 10.1039/C3RA46553E
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