Basic isoreticular nanoporous metal–organic framework for Biginelli and Hantzsch coupling: IRMOF-3 as a green and recoverable heterogeneous catalyst in solvent-free conditions

Abstract

The IRMOF-3 metal–organic framework (MOF) acts as a suitable green catalyst for the one-pot synthesis of dihydropyrimidinone and dihydropyridine derivatives through the Biginelli and Hantzsch reactions, and the desired products were obtained in high yields with short reaction times under mild solvent-free conditions. The MOFs can be isolated from the reaction mixture and reused.