Issue 20, 2014
From the journal:

RSC Advances

Fluorescent nitric oxide detection using cobalt substituted myoglobin†

Trevor D. Rapson,*a   Helen Dacresa  and  Stephen C. Trowella  

* Corresponding authors

a CSIRO Ecosystem Sciences and Food Futures Flagship, GPO Box 1700, ACT, Australia
E-mail: trevor.rapson@csiro.au
Fax: +61 2 62464000
Tel: +61 2 62464104

Abstract

We report two advances in optical biosensing of nitric oxide (NO). Firstly, we developed an improved biomolecular gated system for fluorescent transduction of heme–NO binding. Secondly, through a cobalt substitution, the detection limit for NO was decreased an order of magnitude lower than that of native myoglobin.

Graphical abstract: Fluorescent nitric oxide detection using cobalt substituted myoglobin

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Article information

DOI
https://doi.org/10.1039/C3RA47658H
Article type
Communication
Submitted
16 Dec 2013
Accepted
31 Jan 2014
First published
03 Feb 2014
This article is Open Access
Creative Commons BY license

RSC Adv., 2014,4, 10269-10272

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Fluorescent nitric oxide detection using cobalt substituted myoglobin

T. D. Rapson, H. Dacres and S. C. Trowell, RSC Adv., 2014, 4, 10269 DOI: 10.1039/C3RA47658H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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