Issue 22, 2014

Pd-catalyzed ligand-free Suzuki reaction of β-substituted allylic halides with arylboronic acids in water

Abstract

The catalyst system consisting of Pd(TFA)2 and KOH allows for a wide range of β-substituted allylic halides to react efficiently with various arylboronic acids in neat water under ligand-free conditions, affording the allylated arenes in high yields with broad functional group tolerance and up to 7.4 × 105 TON and 15 416 h−1 TOF.

Graphical abstract: Pd-catalyzed ligand-free Suzuki reaction of β-substituted allylic halides with arylboronic acids in water

Supplementary files

Article information

Article type
Communication
Submitted
20 Dec 2013
Accepted
11 Feb 2014
First published
11 Feb 2014

RSC Adv., 2014,4, 11152-11158

Author version available

Pd-catalyzed ligand-free Suzuki reaction of β-substituted allylic halides with arylboronic acids in water

C. Dong, L. Zhang, X. Xue, H. Li, Z. Yu, W. Tang and L. Xu, RSC Adv., 2014, 4, 11152 DOI: 10.1039/C3RA47813K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements