Issue 6, 2013
From the journal:

Chemical Science

Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP†

Ming-Bo Zhou,a   Ren-Jie Song,*a   Xuan-Hui Ouyang,a   Yu Liu,a   Wen-Ting Wei,a   Guo-Bo Denga  and  Jin-Heng Li*a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
E-mail: jhli@hnu.edu.cn, srj0731@hnu.edu.cn
Fax: +86 731 8871 3642
Tel: +86 731 8882 2286

Abstract

A metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP is established for the synthesis of 3-(2-oxoethyl)indolin-2-ones. This method allows 1,2-difunctionalization of the C–C double bond in N-arylacrylamides by simultaneous formation of two C(sp2)–C(sp3) bonds.

Graphical abstract: Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3SC50810B
Article type
Edge Article
Submitted
26 Mar 2013
Accepted
17 Apr 2013
First published
17 Apr 2013

Chem. Sci., 2013,4, 2690-2694

Permissions

Request permissions

Metal-free oxidative tandem coupling of activated alkenes with carbonyl C(sp2)–H bonds and aryl C(sp2)–H bonds using TBHP

M. Zhou, R. Song, X. Ouyang, Y. Liu, W. Wei, G. Deng and J. Li, Chem. Sci., 2013, 4, 2690 DOI: 10.1039/C3SC50810B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements