Issue 5, 2014

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

Abstract

Nine very bright europium(III) complexes with different macrocyclic ligands have been prepared that exhibit excellent cell uptake behaviour and distinctive sub-cellular localisation profiles, allowing the use of fluorescence microscopy and time-gated spectral imaging to track their fate in cellulo. Their use as cellular imaging stains is described for the selective illumination of mitochondria, lysosomes or the endoplasmic reticulum of various mammalian cell types.

Graphical abstract: EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

Supplementary files

Article information

Article type
Edge Article
Submitted
05 Nov 2013
Accepted
11 Dec 2013
First published
27 Jan 2014

Chem. Sci., 2014,5, 1750-1756

EuroTracker dyes: highly emissive europium complexes as alternative organelle stains for live cell imaging

S. J. Butler, L. Lamarque, R. Pal and D. Parker, Chem. Sci., 2014, 5, 1750 DOI: 10.1039/C3SC53056F

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