Issue 4, 2014

A platform for nitric oxide delivery

Abstract

Nitric oxide (NO) is one of the structurally smallest pharmaceutical molecules, which shows great potential as an anti-restenosis, wound healing, anticancer, and antibacterial agent. To date, while most of the studies have focused mainly on demonstrating the versatility of the NO-releasing materials, little effort has been made on developing successful NO-delivery strategies for advancing NO-mediated therapy. Thus, the quest for a rationally designed NO-delivery system is becoming one of the important issues in the biomedical applications of NO. This feature article discusses the overall research trends in the NO-delivery, focusing mainly on the various particle-type and coating platforms. The objective of this article is not only to highlight the fundamental principle and challenges associated with NO-delivery, but also to provide insight for the further development of novel NO-delivery platforms for clinical applications in the near future.

Graphical abstract: A platform for nitric oxide delivery

Article information

Article type
Feature Article
Submitted
12 Sep 2013
Accepted
28 Oct 2013
First published
29 Oct 2013

J. Mater. Chem. B, 2014,2, 341-356

A platform for nitric oxide delivery

J. Kim, G. Saravanakumar, H. W. Choi, D. Park and W. J. Kim, J. Mater. Chem. B, 2014, 2, 341 DOI: 10.1039/C3TB21259A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements