Issue 11, 2015

Aptamer conjugated silver nanoparticles for the colorimetric detection of arsenic ions using response surface methodology

Abstract

In this study, aptamer conjugated silver nanoparticles (Apt-SNPs) were synthesized and studied for colorimetric sensing of As(III) ions in solution. As(III) ions specifically interact with Apt-SNPs to form As(III)–Apt-SNPs and cause a remarkable decrease in the absorbance peak of silver nanoparticles at 403 nm, which enables the determination of As(III) with high selectivity and sensitivity. A three-factor, central composite design (CCD) optimization method combined with response surface methodology (RSM) was employed to maximize the efficiency of arsenic detection. The significance of the independent variables and their interactions were tested using the analysis of variance (ANOVA). The linear dynamic range of the colorimetric Apt-SNP based optical sensor covered a large variation of As(III) concentration from 50 to 700 μg L−1 and a detection limit of 6 μg L−1 was obtained. Moreover, this assay was able to detect As(III) ions with high sensitivity and revealed to have remarkable potential applications.

Graphical abstract: Aptamer conjugated silver nanoparticles for the colorimetric detection of arsenic ions using response surface methodology

Article information

Article type
Paper
Submitted
08 Dec 2014
Accepted
23 Apr 2015
First published
24 Apr 2015

Anal. Methods, 2015,7, 4568-4576

Author version available

Aptamer conjugated silver nanoparticles for the colorimetric detection of arsenic ions using response surface methodology

F. Divsar, K. Habibzadeh, S. Shariati and M. Shahriarinour, Anal. Methods, 2015, 7, 4568 DOI: 10.1039/C4AY02914C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements