Issue 57, 2014
From the journal:

Chemical Communications

Cytochrome P450 enzyme functionalized-quantum dots as photocatalysts for drug metabolism†

Xuan Xu,a   Jing Qian,a   Jiachao Yu,a   Yuanjian Zhanga  and  Songqin Liu*a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Southeast University, Nanjing, P. R. China
E-mail: liusq@seu.edu.cn
Fax: +86-25-52090618
Tel: +86-25-52090613

Abstract

On the basis of the photo-induced electron transfer (PET) from CdTe quantum dots (QDs) to cytochrome P450 2C9 (CYP2C9), a light-controlled drug metabolism system was successfully designed by using CYP2C9 functionalized-CdTe QDs as photocatalysts.

Graphical abstract: Cytochrome P450 enzyme functionalized-quantum dots as photocatalysts for drug metabolism

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Article information

DOI
https://doi.org/10.1039/C4CC01717J
Article type
Communication
Submitted
07 Mar 2014
Accepted
01 May 2014
First published
13 May 2014

Chem. Commun., 2014,50, 7607-7610

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Cytochrome P450 enzyme functionalized-quantum dots as photocatalysts for drug metabolism

X. Xu, J. Qian, J. Yu, Y. Zhang and S. Liu, Chem. Commun., 2014, 50, 7607 DOI: 10.1039/C4CC01717J

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