Issue 57, 2014

Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

Abstract

Based on the protective properties of carbon nanoparticles for aptamers against the digestion of nuclease, we have developed a nuclease-assisted target recycling signal amplification method for highly sensitive detection of biomolecules, such as ATP and kanamycin. The high binding specificity between aptamers and targets leads to excellent selectivity of the assay.

Graphical abstract: Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

Supplementary files

Article information

Article type
Communication
Submitted
25 Mar 2014
Accepted
22 May 2014
First published
22 May 2014

Chem. Commun., 2014,50, 7646-7648

Author version available

Carbon nanoparticle-protected aptamers for highly sensitive and selective detection of biomolecules based on nuclease-assisted target recycling signal amplification

X. Lin, L. Cui, Y. Huang, Y. Lin, Y. Xie, Z. Zhu, B. Yin, X. Chen and C. J. Yang, Chem. Commun., 2014, 50, 7646 DOI: 10.1039/C4CC02184C

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