Issue 49, 2014
From the journal:

Chemical Communications

Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds†

Dan Zhao,a   Teng Wanga  and  Jian-Xin Li*a  

* Corresponding authors

a State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, P. R. China
E-mail: lijxnju@nju.edu.cn
Fax: +86-25-83686419
Tel: +86-25-83686419

Abstract

A novel metal-free synthesis of quinazolinones via dual amination of sp3 C–H bonds was developed. The sp3 carbon in methylarenes or adjacent to a heteroatom in DMSO, DMF or DMA was used as the one carbon synthon.

Graphical abstract: Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds

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Article information

DOI
https://doi.org/10.1039/C4CC02648A
Article type
Communication
Submitted
10 Apr 2014
Accepted
02 May 2014
First published
02 May 2014

Chem. Commun., 2014,50, 6471-6474

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Metal-free oxidative synthesis of quinazolinones via dual amination of sp3 C–H bonds

D. Zhao, T. Wang and J. Li, Chem. Commun., 2014, 50, 6471 DOI: 10.1039/C4CC02648A

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