Issue 71, 2014
From the journal:

Chemical Communications

Membrane analysis with amphiphilic carbon dots†

Sukhendu Nandi,a   Ravit Malishev,a   Kaviya Parambath Kootery,a   Yelena Mirsky,b   Sofiya Kolushevab  and  Raz Jelinek*ab  

* Corresponding authors

a Department of Chemistry, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
E-mail: razj@bgu.ac.il
Fax: +972-8-6472943

b Ilse Katz Institute for Nanotechnology, Ben Gurion University of the Negev, Beer Sheva 84105, Israel

Abstract

Newly-synthesized amphiphilic carbon dots were used for spectroscopic analysis and multicolour microscopic imaging of membranes and live cells. We show that Förster resonance energy transfer (FRET) occurred from the amphiphilic carbon dots to different membrane-associated fluorescence acceptors. The amphiphilic carbon dots enabled imaging of membrane disruption by the beta-amyloid peptide.

Graphical abstract: Membrane analysis with amphiphilic carbon dots

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Article information

DOI
https://doi.org/10.1039/C4CC03504F
Article type
Communication
Submitted
09 May 2014
Accepted
18 Jul 2014
First published
18 Jul 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 10299-10302

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Membrane analysis with amphiphilic carbon dots

S. Nandi, R. Malishev, K. Parambath Kootery, Y. Mirsky, S. Kolusheva and R. Jelinek, Chem. Commun., 2014, 50, 10299 DOI: 10.1039/C4CC03504F

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