Issue 60, 2014
From the journal:

Chemical Communications

Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au–ZnO hybrid nanoparticles†

Wen Gao,a   Wenhua Cao,a   Huaibin Zhang,a   Ping Li,a   Kehua Xua  and  Bo Tang*a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Synergetic Innovation Center of Chemical Imaging Functionalized Probes, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P.R. China
E-mail: tangb@sdnu.edu.cn

Abstract

We have developed multifunctional Au–ZnO hybrid nanoparticles (NPs) for targeted induction lysosomal membrane permeabilization (LMP)-dependent apoptosis in cancer cells and real-time imaging.

Graphical abstract: Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au–ZnO hybrid nanoparticles

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Article information

DOI
https://doi.org/10.1039/C4CC03793F
Article type
Communication
Submitted
19 May 2014
Accepted
05 Jun 2014
First published
05 Jun 2014

Chem. Commun., 2014,50, 8117-8120

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Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au–ZnO hybrid nanoparticles

W. Gao, W. Cao, H. Zhang, P. Li, K. Xu and B. Tang, Chem. Commun., 2014, 50, 8117 DOI: 10.1039/C4CC03793F

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