Issue 84, 2014
From the journal:

Chemical Communications

Vesicular aptasensor for the detection of thrombin†

Andreas Müllera  and  Burkhard König*a  

* Corresponding authors

a Institut für Organische Chemie, Universität Regensburg, 93040 Regensburg, Germany
E-mail: burkhard.koenig@ur.de
Fax: +49 943 1717
Tel: +49 943 4575

Abstract

Self-assembled phospholipid vesicles are functionalized with thrombin-binding aptamers using a thiol-click reaction. The resulting aptasensors signal the binding of the analyte to the vesicle surface by changes of the emission properties of membrane co-embedded reporter dyes.

Graphical abstract: Vesicular aptasensor for the detection of thrombin

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Article information

DOI
https://doi.org/10.1039/C4CC05221H
Article type
Communication
Submitted
07 Jul 2014
Accepted
04 Sep 2014
First published
04 Sep 2014
This article is Open Access
Creative Commons BY license

Chem. Commun., 2014,50, 12665-12668

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Vesicular aptasensor for the detection of thrombin

A. Müller and B. König, Chem. Commun., 2014, 50, 12665 DOI: 10.1039/C4CC05221H

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