Issue 83, 2014
From the journal:

Chemical Communications

Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes†

Zhixian Li,a   Yifei Zhang,a   Yechao Su,a   Pingkai Ouyang,b   Jun Ge*a  and  Zheng Liu*a  

* Corresponding authors

a Key Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China
E-mail: junge@mail.tsinghua.edu.cn

b College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 211816, China

Abstract

We report a simple precipitation method for the construction of spatially co-localized multi-enzyme systems based on inorganic nanocrystal–protein complexes. A spatially controlled multi-enzyme system exhibits enhanced overall catalytic performance, allowing for sensitive detection of glucose in solution.

Graphical abstract: Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes

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Article information

DOI
https://doi.org/10.1039/C4CC05478D
Article type
Communication
Submitted
16 Jul 2014
Accepted
22 Aug 2014
First published
27 Aug 2014

Chem. Commun., 2014,50, 12465-12468

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Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes

Z. Li, Y. Zhang, Y. Su, P. Ouyang, J. Ge and Z. Liu, Chem. Commun., 2014, 50, 12465 DOI: 10.1039/C4CC05478D

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