Efficient imidation of C(sp3)–H bonds adjacent to oxygen atoms of aryl ethers under metal-free conditions

Abstract

An intermolecular oxidative C–N formation reaction of aryl ethers with pharmacological saccharins was realized under metal-free conditions for the first time. The understanding of the intrinsic characteristics between C(sp³)–H and C(sp²)–O bonds of aryl ethers and their potential for application might promote more research interest in this area.