Issue 87, 2014
From the journal:

Chemical Communications

A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers†

Rishi Sharma,a   Naresh Kottari,a   Yoann M. Chabre,a   Leïla Abbassi,a   Tze Chieh Shiaoa  and  René Roy*a  

* Corresponding authors

a Pharmaqam, Department of Chemistry, University of Quebec a Montreal, C.P. 8888, Succ. Centre-Ville, Montreal, Quebec, Canada H3C 3P8
E-mail: roy.rene@uqam.ca

Abstract

Both convergent and divergent strategies for the synthesis of “onion peel” glycodendrimers are reported which resulted in one of the best multivalent ligands known against the virulent factor from a bacterial lectin isolated from Pseudomonas aeruginosa.

Graphical abstract: A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

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Article information

DOI
https://doi.org/10.1039/C4CC06191H
Article type
Communication
Submitted
07 Aug 2014
Accepted
04 Sep 2014
First published
04 Sep 2014

Chem. Commun., 2014,50, 13300-13303

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A highly versatile convergent/divergent “onion peel” synthetic strategy toward potent multivalent glycodendrimers

R. Sharma, N. Kottari, Y. M. Chabre, L. Abbassi, T. C. Shiao and R. Roy, Chem. Commun., 2014, 50, 13300 DOI: 10.1039/C4CC06191H

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