Issue 83, 2014
From the journal:

Chemical Communications

Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol†

Huai-Rong Zhang,a   Yin-Zhu Wang,a   Mei-Sheng Wu,a   Qiu-Mei Feng,a   Hai-Wei Shi,a   Hong-Yuan Chena  and  Jing-Juan Xu*a  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
E-mail: xujj@nju.edu.cn
Fax: +86-25-83597294
Tel: +86-25-83597294

Abstract

A novel visual electrochemiluminescence (ECL) analysis strategy for detection of telomerase activity is reported on a microarray chip, with G-quadruplex deoxyribozyme (DNAzyme) and luminol modified Au nanoparticles (NPs) as double-catalytic amplification labels.

Graphical abstract: Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol

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Article information

DOI
https://doi.org/10.1039/C4CC06302C
Article type
Communication
Submitted
11 Aug 2014
Accepted
29 Aug 2014
First published
29 Aug 2014

Chem. Commun., 2014,50, 12575-12577

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Visual electrochemiluminescence detection of telomerase activity based on multifunctional Au nanoparticles modified with G-quadruplex deoxyribozyme and luminol

H. Zhang, Y. Wang, M. Wu, Q. Feng, H. Shi, H. Chen and J. Xu, Chem. Commun., 2014, 50, 12575 DOI: 10.1039/C4CC06302C

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