Construction of DNA logic gates utilizing a H+/Ag+ induced i-motif structure

Yunhua Shi; Hongxia Sun; Junfeng Xiang; Hongbo Chen; Qianfan Yang; Aijiao Guan; Qian Li; Lijia Yu; Yalin Tang

doi:10.1039/C4CC06980C

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Construction of DNA logic gates utilizing a H⁺/Ag⁺ induced i-motif structure†

Yunhua Shi,^ab Hongxia Sun,*^a Junfeng Xiang,^a Hongbo Chen,^a Qianfan Yang,^a Aijiao Guan,^a Qian Li,^a Lijia Yu^ab and Yalin Tang*^a

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* Corresponding authors

^a National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry Chinese Academy of Sciences, Beijing, P. R. China
E-mail: tangyl@iccas.ac.cn, hongxsun@iccas.ac.cn

^b University of the Chinese Academy of Sciences, Beijing, P. R. China

Abstract

A simple technology to construct diverse DNA logic gates (OR and INHIBIT) has been designed utilizing a H⁺ and/or Ag⁺ induced i-motif structure. The logic gates are easily controlled and also show a real time response towards inputs. The research provides a new insight for designing DNA logic gates using an i-motif DNA structure.

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Article information

DOI: https://doi.org/10.1039/C4CC06980C
Article type: Communication
Submitted: 04 Sep 2014
Accepted: 21 Oct 2014
First published: 21 Oct 2014

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Chem. Commun., 2014,50, 15385-15388

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Construction of DNA logic gates utilizing a H⁺/Ag⁺ induced i-motif structure

Y. Shi, H. Sun, J. Xiang, H. Chen, Q. Yang, A. Guan, Q. Li, L. Yu and Y. Tang, Chem. Commun., 2014, 50, 15385 DOI: 10.1039/C4CC06980C

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Chemical Communications