Issue 97, 2014
From the journal:

Chemical Communications

Catalytic activity of a dual-hemin labelled oligonucleotide: conformational dependence and fluorescent DNA sensing†

Quanbo Wang,a   Nan Xu,a   Zhen Gui,b   Jianping Lei,a   Huangxian Ju*a  and  Feng Yan*b  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R. China
E-mail: hxju@nju.edu.cn
Fax: +86 25 83593593
Tel: +86 25 83593593

b Department of Clinical Laboratory, Nanjing Medical University Cancer Hospital & Jiangsu Cancer Hospital, 42 Baiziting Road, Nanjing 210009, P.R. China
E-mail: yanfeng2007@sohu.com

Abstract

The conformation-dependent peroxidase activity of a dual-hemin labelled oligonucleotide was identified and conveniently utilized to design a sensitive homogenous fluorescent method for DNA sensing.

Graphical abstract: Catalytic activity of a dual-hemin labelled oligonucleotide: conformational dependence and fluorescent DNA sensing

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Article information

DOI
https://doi.org/10.1039/C4CC07298G
Article type
Communication
Submitted
16 Sep 2014
Accepted
15 Oct 2014
First published
15 Oct 2014

Chem. Commun., 2014,50, 15362-15365

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Catalytic activity of a dual-hemin labelled oligonucleotide: conformational dependence and fluorescent DNA sensing

Q. Wang, N. Xu, Z. Gui, J. Lei, H. Ju and F. Yan, Chem. Commun., 2014, 50, 15362 DOI: 10.1039/C4CC07298G

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