Issue 97, 2014
From the journal:

Chemical Communications

A ratiometric fluorescent probe with unexpected high selectivity for ATP and its application in cell imaging†

Jia-Liang Tang,a   Chun-Yan Li,*a   Yong-Fei Lib  and  Chun-Xiang Zoua  

* Corresponding authors

a Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, P. R. China
E-mail: lichunyan79@sina.com
Fax: +86 731 58292477
Tel: +86 731 58292205

b College of Chemical Engineering, Xiangtan University, Xiangtan, P. R. China

Abstract

Naphthalimide–rhodamine compound (NR) is developed as a ratiometric fluorescent probe for ATP detection based on the FRET mechanism. It shows an unexpected high selectivity for ATP over other anions, especially organic phosphate anions, due to simultaneous interactions of two recognition sites, which benefits fluorescence imaging in living cells.

Graphical abstract: A ratiometric fluorescent probe with unexpected high selectivity for ATP and its application in cell imaging

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Article information

DOI
https://doi.org/10.1039/C4CC08044K
Article type
Communication
Submitted
11 Oct 2014
Accepted
21 Oct 2014
First published
21 Oct 2014

Chem. Commun., 2014,50, 15411-15414

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A ratiometric fluorescent probe with unexpected high selectivity for ATP and its application in cell imaging

J. Tang, C. Li, Y. Li and C. Zou, Chem. Commun., 2014, 50, 15411 DOI: 10.1039/C4CC08044K

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