Issue 19, 2015
From the journal:

Chemical Communications

The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications†

Dongdong Su,a   Chai Lean Teoh,a   Animesh Samanta,a   Nam-Young Kang,a   Sung-Jin Parka  and  Young-Tae Chang*ab  

* Corresponding authors

a Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore

b Department of Chemistry & MedChem Program of Life Sciences Institute, National University of Singapore, Singapore
E-mail: chmcyt@nus.edu.sg

Abstract

A novel zwitterionic near-infrared (NIR) dye, ZWCC, has been designed and synthesized. It shows significantly enhanced photostability and chemical stability compared to the existing zwitterionic NIR dye. In addition, the feasibility of labeling ZWCC with biological ligands was investigated and used in live cell imaging applications.

Graphical abstract: The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications

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Article information

DOI
https://doi.org/10.1039/C4CC08814J
Article type
Communication
Submitted
05 Nov 2014
Accepted
28 Jan 2015
First published
29 Jan 2015

Chem. Commun., 2015,51, 3989-3992

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The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications

D. Su, C. L. Teoh, A. Samanta, N. Kang, S. Park and Y. Chang, Chem. Commun., 2015, 51, 3989 DOI: 10.1039/C4CC08814J

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