A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity

Hongxing Zhang; Jing Liu; Yuan-Qiang Sun; Yingying Huo; Yaohua Li; Weizhi Liu; Xiao Wu; Nishu Zhu; Yawei Shi; Wei Guo

doi:10.1039/C4CC09122A

A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity†

Hongxing Zhang,‡^a Jing Liu,‡^a Yuan-Qiang Sun,^a Yingying Huo,^a Yaohua Li,^a Weizhi Liu,^a Xiao Wu,^a Nishu Zhu,^a Yawei Shi^b and Wei Guo*^a

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^a School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
E-mail: guow@sxu.edu.cn

^b Institute of Biotechnology, Shanxi University, Taiyuan 030006, China

Abstract

A mitochondria-targetable fluorescence probe, methyl(4-hydroxyphenyl)amino-substituted pyronin (1), was exploited, which could highly selectively sense peroxynitrite (ONOO⁻) within seconds.

Chemical Communications

A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity†

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A mitochondria-targetable fluorescent probe for peroxynitrite: fast response and high selectivity

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