Issue 6, 2015

A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

Abstract

A new strategy for the synthesis of epoxides is presented. This process allows the direct synthesis of epoxides from alkenes and aldehydes through C–H functionalization and C–C/C–O bond formation.

Graphical abstract: A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

Supplementary files

Article information

Article type
Communication
Submitted
20 Nov 2014
Accepted
27 Nov 2014
First published
27 Nov 2014

Chem. Commun., 2015,51, 1012-1015

Author version available

A transition-metal-free, one-pot procedure for the synthesis of α,β-epoxy ketones by oxidative coupling of alkenes and aldehydes via base catalysis

Q. Ke, B. Zhang, B. Hu, Y. Jin and G. Lu, Chem. Commun., 2015, 51, 1012 DOI: 10.1039/C4CC09260K

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