Issue 12, 2015

A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging

Abstract

We report a two-photon fluorescent probe for ratiometric imaging of cysteamine in situ. This probe can detect the levels of endogenous cysteamine with statistical significance in live cells and brain hippocampal tissues, revealing that cysteamine is localized mainly in the perikaria of the pyramidal neurons and the granule cells.

Graphical abstract: A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging

Supplementary files

Article information

Article type
Communication
Submitted
25 Nov 2014
Accepted
17 Dec 2014
First published
22 Dec 2014

Chem. Commun., 2015,51, 2407-2410

A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging

A. R. Sarkar, C. H. Heo, E. Kim, H. W. Lee, H. Singh, J. J. Kim, H. Kang, C. Kang and H. M. Kim, Chem. Commun., 2015, 51, 2407 DOI: 10.1039/C4CC09416F

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