Synthesis of a mixed valence state Ce-MOF as an oxidase mimetic for the colorimetric detection of biothiols

Abstract

We demonstrate a facile and rapid in situ partial oxidation synthetic strategy for the fabrication of a mixed valence state Ce-MOF (MVCM) which exhibits intrinsic oxidase-like activity. Furthermore, on the basis of the excellent catalytic activity of the MCVM, a colorimetric approach for the high-throughput detection of biothiols in serum samples was established.