Detection of the nanomolar level of total Cr[(III) and (VI)] by functionalized gold nanoparticles and a smartphone with the assistance of theoretical calculation models

Wenwen Chen; Fengjing Cao; Wenshu Zheng; Yue Tian; Yunlei Xianyu; Peng Xu; Wei Zhang; Zhuo Wang; Ke Deng; Xingyu Jiang

doi:10.1039/C4NR06726F

Detection of the nanomolar level of total Cr[(iii) and (vi)] by functionalized gold nanoparticles and a smartphone with the assistance of theoretical calculation models†

Wenwen Chen,^ab Fengjing Cao,^a Wenshu Zheng,^ab Yue Tian,^a Yunlei Xianyu,^ab Peng Xu,^c Wei Zhang,^a Zhuo Wang,*^a Ke Deng*^d and Xingyu Jiang*^a

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* Corresponding authors

^a Beijing Engineering Research Center for BioNanotechnology & Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
E-mail: xingyujiang@nanoctr.cn, wangz@nanoctr.cn

^b University of Chinese Academy of Sciences, Beijing 100049, China

^c Nano Measurement Laboratory, National Center for Nanoscience and Technology, Beijing 100190, China

^d CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, Beijing 100190, China

Abstract

We report a method for rapid, effective detection of both Cr(III) and Cr(VI) (in the form of Cr³⁺ and Cr₂O₇²⁻, the main species of chromium in the natural environment) by making use of meso-2,3-dimercaptosuccinic acid (DMSA)-functionalized gold nanoparticles (Au NPs). The limit of detection (LOD) is 10 nM with the naked eye and the assay can be applied in detecting chromium in polluted soil from Yun-Nan Province in Southwest China. We use density functional theory to calculate the change of the Gibbs free energy (ΔG) of the interactions between the DMSA-Au NP system and various metal ions, which shows that DMSA-Au NPs have high specificity for both Cr³⁺ and Cr₂O₇²⁻.

Nanoscale

Detection of the nanomolar level of total Cr[(iii) and (vi)] by functionalized gold nanoparticles and a smartphone with the assistance of theoretical calculation models†

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Detection of the nanomolar level of total Cr[(III) and (VI)] by functionalized gold nanoparticles and a smartphone with the assistance of theoretical calculation models

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