Issue 27, 2014

Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Abstract

Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

Graphical abstract: Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Supplementary files

Article information

Article type
Communication
Submitted
10 May 2014
Accepted
30 May 2014
First published
30 May 2014

Org. Biomol. Chem., 2014,12, 4828-4831

Author version available

Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

S. Huang, L. Ma, M. H. Tong, Y. Yu, D. O'Hagan and H. Deng, Org. Biomol. Chem., 2014, 12, 4828 DOI: 10.1039/C4OB00970C

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