A novel label-free fluorescent biosensor platform has been developed for protease activity assay using peptide-templated gold nanoclusters (AuNCs). The biosensor was demonstrated with elastase as the model to have high sensitivity, excellent specificity, simplicity and rapidity.
Y. Gu, Q. Wen, Y. Kuang, L. Tang and J. Jiang, RSC Adv., 2014, 4, 13753 DOI: 10.1039/C4RA00096J
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