Issue 49, 2014

Hypervalent iodine(iii) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles

Abstract

An iodine(III) catalyzed C(sp2)–H functionalization–intramolecular amination reaction of N-aryl-2-amino-N-heterocycles has been developed in water and under ambient conditions. This metal-free open-flask chemistry is general and successfully applied in synthesizing the benzimidazole-fused heterocycles pyrido[1,2-a]benzimidazole, benzimidazo[1,2-a]quinoline and benzimidazo[2,1-a]isoquinoline derivatives.

Graphical abstract: Hypervalent iodine(iii) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles

Supplementary files

Article information

Article type
Communication
Submitted
15 Mar 2014
Accepted
26 Apr 2014
First published
28 Apr 2014

RSC Adv., 2014,4, 25600-25604

Author version available

Hypervalent iodine(III) catalyzed oxidative C–N bond formation in water: synthesis of benzimidazole-fused heterocycles

D. N. Rao, Sk. Rasheed, R. A. Vishwakarma and P. Das, RSC Adv., 2014, 4, 25600 DOI: 10.1039/C4RA02279C

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