As a green and inexpensive biocatalyst, lipase has been used to catalyze the synthesis of 3,3′-(arylmethylene)bis(2-hydroxynaphthalene-1,4-dione) (3) for the first time. The products could be obtained in excellent yields (82.2–94.8%, 2 h). This study not only provides a simple and efficient method, but also expands the biocatalytic promiscuity of lipase in organic synthesis.
H. Wang, Z. Wang, C. Wang, F. Yang, H. Zhang, H. Yue and L. Wang, RSC Adv., 2014, 4, 35686 DOI: 10.1039/C4RA06516F
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