Polyvinylpyrrolidone-stabilized magnetic nickel nanochains for cancer hyperthermia and catalysis applications

Abstract

In this study, we report a novel polyvinylpyrrolidone-stabilized magnetic nickel nanochain (Ni-NC@PVP) using a simple solvothermal method for potential cancer hyperthermia and catalytic applications. The water-soluble Ni-NC@PVP exhibits excellent magnetic hyperthermia properties and low toxicity. In order to investigate the apoptotic hyperthermia efficacy of Ni-NC@PVP in skin cancer cells, we also explore the interaction of Ni-NC@PVP with cancer cells, which exhibits excellent antitumor efficacy on B16 cells. In addition, as a magnetically separable catalyst, it also shows excellent catalytic activity and durability for the selective hydrogenation of acetophenone to 1-phenylethanol. The enhanced performance demonstrates the possibility for designing new multifunctional nanomaterial with improved performances for biomedical therapies and green catalysis.