Issue 110, 2014

Metal-free oxidative coupling of amines with sodium sulfinates: a mild access to sulfonamides

Abstract

A practical and mild procedure for the preparation of sulfonamides through TBAI-catalyzed oxidative coupling of amines with sodium sulfinates using TBHP as an oxidant was presented. A variety of amines and sodium sulfinates could go through the transformation, without impacting the hydroxyl group.

Graphical abstract: Metal-free oxidative coupling of amines with sodium sulfinates: a mild access to sulfonamides

Supplementary files

Article information

Article type
Communication
Submitted
30 Oct 2014
Accepted
21 Nov 2014
First published
21 Nov 2014

RSC Adv., 2014,4, 64698-64701

Author version available

Metal-free oxidative coupling of amines with sodium sulfinates: a mild access to sulfonamides

J. Zhao, J. Xu, J. Chen, X. Wang and M. He, RSC Adv., 2014, 4, 64698 DOI: 10.1039/C4RA13454K

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